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In some in-vitro studies, fibroblast cultures exposed to AHK-Cu complexes appeared to show an increase in collagen type I production, with reports of increases as high as 300% over controls

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Growth hormone therapy can induce insulin resistance, elevate fasting glucose, worsen glycemic control in diabetics or pre-diabetics, increase risk of developing type 2 diabetes with long-term use, and require medication adjustments for individuals with existing diabetes

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