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So I want to walk through what we actually know about the science, the access question, and the wider context that any honest conversation about obesity drugs has to sit within

But patients who jump doses, who go from 2.5mg straight to 7.5mg, or who escalate every two weeks instead of every four, report significantly worse GI symptoms that sometimes require medical intervention

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otherwise, they can lead to gastrointestinal tract symptoms like nausea, vomiting, diarrhea, and other toxic effects