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The rapid weight regain during medication-free periods may offset any theoretical benefits

Bowel obstruction : Some have reported blocked intestines, causing severe abdominal pain, nausea, and vomiting

Unfamiliarity with withdrawing medication from a vial into a syringe and coupled with confusion between different units of measurement (e.g., milliliters, milligrams and units) may have contributed to dosing errors

Stopping all at once can make appetite return quickly and may lead to blood sugar swings if you have diabetes

That means a licensed clinician prescribes them for the "diagnosis, cure, mitigation, treatment, or prevention" of a disease