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For example, they dont measure consumption of illicit cigarettes, cross-border purchases or duty free shopping

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Together, they create an environment where smoking is less visible, less socially acceptable and less desirable, leading to lower smoking rates and improved public health outcomes

While conventional pulmonary function testing remains the cornerstone of diagnosing airflow limitation, its sensitivity for early detection of SAD is insufficient ( Physiological characteristics of the small airway Small airways are defined as those with a diameter of less than 2 mm and are considered part of the distal airway system, comprising membranous bronchioles, respiratory bronchioles, and alveolar ducts ( Initiation phase Epithelial damageEMT (epithelial-mesenchymal transition)impaired barrier functionmucus obstruction The small airway epithelium is the main defense barrier of the respiratory tract against inhaled harmful particles and pathogens