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Diabetes, especially when poorly controlled, can damage blood vessels and increase the risk of heart disease and stroke

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As a proof of concept, and due to the relative ease of induction and assessment of differentiation in MSCs, the difficulty in obtaining organ-specific stem cells, and the fact that MSCs are recruited to sites of injury for tissue repair, the well-established model of MSC differentiation into osteoblast-like cells was used to assess the effects of smoke extracts on the differentiation potential of MSCs