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Also, studies have shown that nicotine treatment helps improves the clinical signs of Tourettes syndrome as well as delay the progression of Parkinsons disease

The genetic instrument for CSI comprised by 90 SNPs with independent and robust associations with the lifetime smoking exposure indicator was associated with the risk of both HPV-negative HNSCC [IVW OR (95% CI) = 2.59 (1.37, 4.92), P = 0.0004] and HPV-positive HNSCC [IVW OR (95% CI) = 2.6 (1.2, 5.65), P = 0.02]

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And I screwed that up. Angie would be Angelina Jolie