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14.10 Postmarketing Neuropsychiatric Safety Outcome Trial CHANTIX was evaluated in a randomized, double-blind, active and placebo-controlled trial that included subjects without a history of psychiatric disorder (non-psychiatric cohort, N=3912) and with a history of psychiatric disorder (psychiatric cohort, N=4003)

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The higher your score, the more dependent you are and the higher the initial dosage should be when you start replacement treatment