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The Surging Popularity of GLP-1s By 2024, approximately 4% of Americans were taking a GLP-1 receptor agonist for weight loss, obesity, or type 2 diabetesa staggering 600% increase since 2018

In a series of further experiments, we identified that Efavirenz dysregulated ER stress and autophagy by blocking the activity of the Beclin-1/Atg14/PI3KIII complex in regard to synthesis of phosphatidylinositol 3-phosphate (PI3P), a process which is linked to the formation of autophagosomes