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Bjurlin and colleagues also characterized three potential flavoring compounds that showed higher levels in e-cigarette users than in smokers and controls: ethyl levulinate, delta-decalactone, and gamma-heptalactone: In addition, e-cigarette users had the highest urinary level of diethylphthalate among the three groups, while smokers also showed elevated exposure in their urine: With regards to the presence of carcinogens and cancer-related biomarkers, they found that Me-Fapy (the monitoring of which may imply the level of alkylating DNA damage) showed a significant elevated in the urine samples of smokers compared to control, whereas for e-cigarette users there was a weak statistical trend

However: The appetite suppression effect is mild and inconsistent across individuals