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That makes it more difficult for chemotherapy to do the job of killing cancer cells. Smoking makes it harder for your body to recover from cancer treatment, especially those that involve surgery

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When dissolved in a solution, that nicotine can enter the body directly through the skin

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Also, as noted above, it is well-established that smokers smoke to control the delivery of nicotine, not tar (TPM) [98][100] and normalizing toxin deliveries by nicotine delivery yields higher toxicity estimates than normalizing by TPM (Figures 24