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8 Department of Respiratory Medicine, Private clinics Musumeci-Gecas, Catania, Italy *These authors contributed equally to this work Background: Health effects of electronic cigarette (EC) use in patients with chronic obstructive pulmonary disease (COPD) are largely unexplored

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Patients with original comorbidities, including cardiovascular disease, cancer, kidney and liver diseases, diabetes mellitus, hypertension, tuberculosis, venous thromboembolism, and older adults, are high-risk cases for COVID-19 infection [32]