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[12] Nevertheless, individuals with conditions affecting copper metabolism such as Wilson's disease should seek specialist medical advice before use

10.1080/15548627.2016.1187366 39 HuQ.ZuoT.DengL.ChenS.YuW.LiuS.et al (2022)

Moreover, mice as well as humans with reduced activity of the GH/IGF-1 axis are protected from cancer and diabetes mellitus, two major ageing-related morbidities

Evidence Evidence that CFS/ME patients are low in methylation cycle metabolites: B vitamin evidence In a small study of 58 chronic fatigue syndrome patients with a history of Epstein-Barr infection and B-cell immunodeficiency, 81% responded to folinic acid

Without it, you are essentially paying for a supplement that your body cannot fully use