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For cognitive impairment, FDA-approved options include donepezil and the newer anti-amyloid antibodies for Alzheimer disease

doi: 10.1097/01.AOG.0000280587.02443.75

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Furthermore, the anti-obesity properties of carnitine might be attributed to its potential role in stimulating adipocyte lipolysis, through upregulating lipolytic gene expression, namely, hormone-sensitive lipase (HSL) (21), carnitine palmitoyl transferase Ia (CPT-Ia) (21), and acyl coenzyme A oxidase (ACO) (21), as well as attenuating adipogenesis in adipocytes through suppression of adipogenic gene expression, including peroxisome proliferator-activated receptor gamma (PPAR-) and adipose-specific fatty acid-binding protein (aP2) in adipose tissue (21)

1999;277(5 Pt 1):E78491