Physical barrier is also maintained by mucociliary barrier comprising cilia, a periciliary fluid layer (sol), and a mucus layer (gel)
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According to the World Health Organization (WHO), 4,500 billion cigarette butts out of the 6,000 billion cigarettes consumed are thrown on the ground each year
Heat-not-burn tobacco products first became commercially available in the 2010s as an alternative to combustible tobacco cigarettes, addressing many of the weaknesses of e-cigarettes which deliver nicotine through vapour instead of smoke
It also found that the risk of a 1 to 4 cigarette smoker developing lung cancer was 2.79 times greater in men and a disturbing 5 times higher in women (5.03)