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Olde Rikkert MG, Verhey FR, Sijben JW, Bouwman FH, Dautzenberg PL, Lansink M et al

This aligns with a mechanistic view that GLP-1 RAs might improve endothelial nitric oxide and penile blood flow

Therefore, although there is no apparent evidence at the current time for overlapping mechanisms between the development of NAION and nAMD, it may be interesting to consider the involvement from impaired ocular blood flow (probably based on hypoperfusion of SPCAs) as a possible common mechanism of both conditions, and to investigate if GLP-1RAs or GIP/GLP-1RA (tirzepatide) can affect directly or indirectly the perfusion of SPCAs and choroidal capillaries

Phenotype-genotype correlations in patients with Wilsons disease

4. How long will one bottle last