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Thus, according to the cytokine hypothesis, it is reasonable to believe that these pro-inflammatory cytokines can then increase the risk of depression through ways such as inhibiting the negative feedback of the HPA axis, increasing the permeability of the BBB, and so on

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Nicotine toxidrome: biphasic progression of nicotine toxicity

Future studies should explore glycocalyx regeneration and its role in SAP-associated MODS to achieve better clinical outcomes