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Effect of combination therapy with thyroxine (T4) and 3,5,3-triiodothyronine versus T4 monotherapy in patients with hypothyroidism, a double-blind, randomised cross-over study
Researchers have observed this protective effect through glutathiones activation of the Nrf2/HO-1 signaling pathway [4]
Such inhibitors bind reversibly but dissociate from the enzyme slowly thereby exhibiting extended duration despite their short t1/2 values
R., Cianfarani, S., Cappa, M., & Fintini, D
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