(e) cross-sectional studies with no time restriction, (f) only studies published in English were included due to resource limitations and to ensure accuracy in data extraction and risk-of-bias assessment
Putting the evidence side by side Here is the blunt comparison: AOD 9604: 2.6 kg weight loss in 12 weeks (best result), failed six clinical trials, development terminated Semaglutide: 15 to 17 percent body weight loss over 68 weeks, FDA approved, thousands of study participants, consistent results across multiple trials There is no way to frame this comparison that puts AOD 9604 on equal footing with semaglutide when it comes to clinical evidence
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Very high doses may occasionally cause hypokalaemia (low potassium), particularly in patients with severe megaloblastic anaemia when treatment is initiated, necessitating monitoring in hospital settings