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Model validation MR-BRT has been extensively and rigorously validated by Zheng and colleagues for its use in conducting meta-analyses 18

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Similar to the well-established concept of pack years in the literature for cigarette smoking, the betel year serves as a clinical quantification tool to assess an individuals lifetime exposure to betel quid chewing

All things are lawful for me, but I will not be dominated by anything. Assuming theres no illegality, I think its fair to say that a substance is generally neutral in itself, and that the morality of the issue depends largely on the user, his or her attitude, motives, and desires

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