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About 80 percent of adult smokers first try smoking by age 18, according to the CDC

Altria's net revenues for the first quarter decreased 5.7% to $5.3 billion, primarily driven by lower net revenues in the smokeable products segment, the tobacco company reported during its first-quarter 2025 earnings call on Tuesday

Cyanide from tobacco alkaloids is present in tobacco smoke, thus leading to a modest chronic exposure in the smoke [7]

Again, results for 3OH-cotinine were similar to cotinine (adjusted R 2 men 0.31, women 0.35) (Table S2, additional file 1)

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