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doi: 10.1177/001789690406300307 67

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First, lets talk about some general adverse effects of the mix: Increased Drowsiness and Fatigue: Both Lexapro and cannabis can cause drowsiness, and using them together may amplify this effect, potentially impacting alertness and energy levels

The incidence varied from one study to another, depending on the dosage, route of administration, use of other central-nervous-system depressants, and the investigator's opinion concerning the degree and duration of desired sedation