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Further, on May 20, 2022, the Company received notification of the FDA's filing of its bundled PMTA, which reflected the FDA's determination that the Company's PMTA "is sufficiently complete to enter [the] substantive review phase." The Company does not use synthetic nicotine in its products, and therefore the recent federal legislation subjecting synthetic nicotine products to FDA regulation does not impact any of Black Buffalo's products

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has increased sixfold since 1999 and overdoses now claim more than 115 lives every day, according to National Institute on Drug Abuse research

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