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Volkow puts it, dopamine ensures "long-lasting memory of salient events." A true priority or "wanting" disorder, it's why the dependent user seems deaf to their loved one's pleas to quit, and blind to articles such as this

Minimal evidence showed that motivational interviewing may or may not help people to quit compared with no intervention or compared with other type of behavioral intervention 30

Tobacco smoking was estimated as being responsible for approximately 67,300 premature deaths in Chinese adults aged 40 years and over in 2005 [2]

Davies C, Bhattacharyya S

Overall it appears that women seem to be at higher risk