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The National Institutes of Health support a broad range of research on the cannabinoid system

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Nontypeable Haemophilus influenzae clearance by alveolar macrophages is impaired by exposure to cigarette smoke

Some of these effects are cosmetic, some affect your oral health more broadly, and one connects directly to an issue we've covered before: the same "two-tone" staining problem that makes whitening strips incompatible with traditional braces also applies to smoking except in this case, it's smoke and tar causing the uneven staining rather than a whitening gel