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In this same study, the candidate genes BvHMA3 and BvNRAMP3 showed upregulation patterns in response to Cd-toxicity, suggesting that these candidate genes are involved in Cd uptake processes
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Additionally, this compound exhibits relatively long in vivo half-life characteristics, supporting once-daily dosing regimens and improving patient treatment compliance ( In rodent models, BI 1291583 demonstrated favorable dose-dependent NSP inhibitory effects
N., Ma, R., Pickles, T., Rootman, J
Kato T, Niizuma S, Inuzuka Y, Kawashima T, Okuda J, Tamaki Y, Iwanaga Y, Narazaki M, Matsuda T, Soga T, Kita T, Kimura T, Shioi T (2010) Analysis of metabolic remodeling in compensated left ventricular hypertrophy and heart failure
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