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Rinaman said that her laboratory discovered that the GLP-1 neurons in the rodent hindbrain are suppressedthat is, their ability to be activated is reducedduring states of negative energy balance, for example, after 18 hours of fasting in rats or mice (Maniscalco and Rinaman, 2018)

Selank appears to act as an anxioselective agent reducing anxiety-related behaviors without producing sedation at effective doses in rodent models

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