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British Journal of Nutrition, 105 (11), 1563-1571

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Furthermore, protease-activated receptor 2 (PAR2) signaling in melanocytes amplifies oxidative and inflammatory responses through the Akt/NF-B axis, elevating cytokine production and reducing antioxidant defenses, based on CAT and SOD activity, exacerbating skin inflammation 126

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Adequate intracellular glutathione levels: Phase l: Glutathione synthesis within the cells is an energy-dependent process that requires the availability of multiple functioning enzyme systems, nuclear transcription factors and adequate levels of the amino acids cysteine, glutamine and lysine

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