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In addition, our results were still significant when we compared the non-age-matched groups, including younger patients who smoked marijuana and who presumably had less lifetime exposure to cigarette smoke. The reasons for the differences between the two groups is likely due to several factors

Full-spectrum includes various cannabinoids and terpenes working together, while isolate excludes THC entirely

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Vanilla : Smooth vanilla sweetness with a soft, creamy finish

Also the roll size of the cigarettes was changed into the same size as the general ones, and both the roll and flavor became thicker than before