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One patient was a recurrent case, who had surgery at the age of 45 months (Case 8 in Table 1 )

Transfusion suppresses erythropoiesis and increases hepcidin in adult patients with -thalassemia major: a longitudinal study

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Step 3: Transition to Maintenance Dosing Based on UV Exposure Frequency After completing the 14-day loading phase, maintenance dosing ranges from 0.08mg/kg twice weekly (for minimal UV exposure) to 0.16mg/kg three times weekly (for regular outdoor activity or high-altitude environments where UV intensity is 1012% higher per 1,000 feet of elevation gain)