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Supporting Fetal Development : Adequate antioxidant levels can support the developing fetus by promoting healthy growth and reducing the risk of birth defects

Funding The research was supported in part by Grants-in-Aid for Challenging Exploratory Research and Scientific Research (B) from the Japan Society for the Promotion of Science (JSPS KAKENHI Grant Numbers JP26660218, JP21H02347, and JP24K01911, respectively) and by grant funds from the Uehara Memorial Foundation and Ito Foundation (all to R

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The copper coordination chemistry of GHK-Cu enables controlled cellular copper delivery while preventing the formation of reactive oxygen species characteristic of free copper toxicity, with the peptide's binding affinity (log K = 16.1) positioning it perfectly within the physiological copper transport hierarchy to facilitate controlled metal transfer to enzymatic targets including lysyl oxidase (essential for collagen cross-linking) and superoxide dismutase (critical for antioxidant defense)

These compounds exhibit antioxidant, antimutagenic (impede cell mutation), anti-inflammatory, and anticancer properties