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Like smoking, shisha smoking produces significant levels of noxious chemicals including tar, carbon monoxide (CO), nitric oxide and various carcinogens [footnote 26] [footnote 27]

These events included in the endpoint were adjudicated by a blinded, independent committee

Cancer: Smoking is the leading cause of lung cancer

10.3748/wjg.v18.i18.2180 [DOI] [PMC free article] [PubMed] [Google Scholar] 74.Biedermann L, Zeitz J, Mwinyi J, Sutter-Minder E, Rehman A, Ott SJ, et al