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Chronic injury caused by smoking can lead to two lung conditions: Emphysema: Damage to air sacs in the lungs

See also p.67 of the report: Burning Issues: The Global State of Tobacco Harm Reduction 2020 Continuum of Risk for Nicotine Containing Products - Burning Issues: The Global State of Tobacco Harm Reduction 2020 In the context of tobacco harm reduction what does safer mean

Nicotine pouches thus can provide a significant protection against urges to smoke, and the effect seems to last longer than the effect of a cigarette

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