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Hockney wrote to the Guardian constantly, always with the same message

In fact, extracting and refining petroleum to make plastics and the incineration by which they are often disposed also contribute to climate change these processes accounted for 4.5 percent of global greenhouse gas emissions in 2015

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However, the contribution of the C-terminal E3 ubiquitin ligase RING domain of MDM2 to these oncogenic phenotypes remains unclear