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Short-term effects of smoking on the throat include: Dryness caused by reduced moisture in the throat lining Scratchy or burning sensation during or after smoking Temporary inflammation leading to mild soreness Increased sensitivity to cold air, pollutants, or strong odours Occasional hoarseness or slight changes in voice Long-term smoking can lead to the following effects on the throat: Chronic throat irritation due to repeated exposure to smoke Persistent inflammation that does not fully resolve Ongoing dryness and reduced natural mucus protection Frequent throat clearing linked to irritation or mucus buildup Greater susceptibility to infections due to weakened local defences Prolonged hoarseness or voice strain As time passes, the throat may become less able to recover efficiently, especially with continued smoking

Soleimanifar N, Assadiasl S, Kalateh E, Hassanvand MS, Sadr M, Mojtahedi H, et al

Neutrophils were then washed in Hankss balanced salt solution and further purified using MACS-based neutrophil isolation kit (Milteyni Biotec130-097-658) as per manufacturers recommendation and cultured in serum-free AIM-V medium

regulators still treat it as a tobacco product

The same factsheet also mentions that it is "often used to clean teeth"