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Forensic Sci Int Genet 49:102359

NNMT is a metabolic enzyme that regulates cellular energy and methylation potential by preventing NAM (Nicotinamide) from participating in the NAD+ Salvage Pathway and converting back into NAD+

The objective of this review is to critically assess the current evidence surrounding their mechanisms of action, clinical indications, efficacy, and safety profiles, with particular emphasis on regulatory and translational considerations

At the same time, GLP-1 receptor agonists are being prescribed with increasing frequency for metabolic indications, including in patients with IBD

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