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Aliment Pharmacol Ther 2010;32:377-83

Tirzepatide, a single peptide that binds to both GLP-1 and GIP receptors, was approved by the FDA in 2022 to treat type 2 diabetes

Take the clinical trials for Wegovy as an example: participants with type 2 diabetes lost an average of 3.9% of their body weight within three months, compared to 6.3% in those without diabetes

Are there any risks with combining these treatments

Pineal gland regulation: The tetrapeptide modulates melatonin synthesis in the pineal gland, potentially restoring age-related declines in melatonin production that contribute to disrupted circadian rhythms and reduced antioxidant defense