NADPH is mainly derived from the pentose phosphate pathway, which uses glucose-6-phosphate dehydrogenase (G6PD) as the key enzyme [36]
This compound is a well-known extremolyte a type of small organic molecule that can protect cells under extreme, virtually [un]inhabitable conditions.7 In addition to protecting the skin from intense stress, ectoine also appears to improve the stability of various peptides by strengthening their hydration shell.8 Some research suggests that GHK-Cu (the copper peptide used in most copper peptide products) may have insufficient stability and could be prone to decomposition by skin proteases.9 Theoretically, then, the inclusion of ectoine in Allies of Skin Copper Tripeptide & Ectoin Advanced Repair Serum might be able to promote better stability and efficacy of the peptide
Because B vitamins are water-soluble and the body can't store most of them long-term, regular intake through food (or supplementation when needed) matters more than occasional big doses
For more information, see the Safety section below
Improved Insulin Sensitivity Fourth, NNMT inhibition improves insulin sensitivity and glucose metabolism through multiple mechanisms including increased NAD+ and SIRT1 activity, reduced adipose tissue inflammation, and improved mitochondrial function
