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What we have is a plausible biological hypothesis (collagen peptide supplementation provides the amino acid substrates that bone matrix formation depends on, which may be relevant when those substrates are being depleted by rapid weight loss) supported by a strong positive RCT in a related population - and no direct evidence yet in the GLP-1 therapy population specifically

Among the less commonly discussed adverse effects are alterations in taste perception, including reports of a persistent bad taste in the mouth