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Peptides 13(1):1316 Sandoval DA, DAlessio DA (2015) Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease

It is useful for weight loss through effects on GLP-1 receptor activation, insulin sensitizing affects, and anti-inflammatory effect

Tirzepatide produces slightly greater average weight loss (20-22% vs 10-15%), but both medications work through similar mechanisms

Individual results are not guaranteed

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