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The two main culprits here are cortisol (the primary stress hormone) and prolactin
In eight studies in which the effects of smoking cessation on endothelial function were assessed by biomarkers[19, 20, 23, 24, 30, 31, 92, 93], five studies showed that smoking cessation increased or improved biomarkers for endothelial function including circulating levels of nitrate/nitrite, NO, vvWF, ICAM-1, EPCs and EMPs and activity of eNOS [19, 23, 24, 30, 31]
This is often measured through alcohol breath tests, blood tests, and alcohol urine tests
However, if reflux is frequent and severe it needs to be addressed
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