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While GLP-1 receptor agonists, including medications like Ozempic, Wegovy, and Mounjaro, have become central to the management of metabolic health, a growing body of research suggests their impact may extend into addiction medicine

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POMC-derived peptides including adrenocorticotropin (ACTH), alpha melanocyte stimulating hormone (-MSH), -MSH and -endorphins, MC1R, adrenergic and cholinergic agents, and growth factors, cytokines, or nitric oxide (NO) secreted in the local microenvironment are all involved in the regulation of melanogenesis [6]

Nonetheless, it is not certain whether EA may be helpful in boosting the GSH system in cardiac patients and treating heart diseases