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The engineered strain W303-1b/FGP with three biosynthetic pathways presented the highest GSH concentration (216.50 mg/L) and GSH production of W303-1b/FGP was further improved by 61.37 % when amino acid precursors (5 mM glutamic acid, 5 mM cysteine and 5 mM glycine) were fed in shake flask cultures

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FIGURE 3 Targeting peptides protected keratinocytes against H 2 O 2 damage We tested the cytotoxicity of peptides at different concentrations on two human skin cell lines that were mainly distributed in the epidermis and dermis layers

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Requires Daily Dosing: Oral supplements often need to be taken daily, as the body absorbs smaller amounts at a time