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Acknowledgements We acknowledge the SSGAC Consortium ( IEU OpenGWAS project database ( and FinnGen database ( for providing GWAS summary-level statistics

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Figure 1: Odds Ratios (OR) of lung cancer in chronic smokers who vaped versus chronic smokers who did not vape by gender, histologic cell type (SCC: Squamous Cell Carcinoma, AC: Adenocarcinoma) and pack-years (PY) of cigarette smoking