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Cited studies are preclinical research, not therapeutic claims

Larger, medication-controlled studies are needed to clarify whether synaptic loss is a core feature of LLD, is associated with A and Tau and whether synaptic loss marks a subgroup at risk for persistent symptoms and cognitive decline, as is the focus of an ongoing study [249]

It is understood that a deficiency of acetyl-L-carnitine could play a role in developing depressive symptoms (4)

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