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For those on GLP-1 medications, such as semaglutide (Wegovy or Ozempic), incorporating weightlifting, creatine supplementation, and a high-protein diet can amplify results by preserving muscle mass, enhancing metabolism, and promoting satiety

Importantly, SGLT1 knockdown further enhanced the regulatory effects of XBP on myocardial energy metabolism, whereas SGLT1 overexpression reversed its cardioprotective effects, confirming that SGLT1 is a key molecular target in the improvement of XBP-mediated FAO