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Importantly, the odds of ION risk in patients was shown to be nearly five times higher with Wegovy than it was with Ozempic

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Decades later, the United Kingdom Prospective Diabetes Study (UKPDS) 18 documented significant microvascular benefit for patients with new-onset T2DM randomized to intensive glycemic control with insulin or a sulfonylurea compared to patients using conventional therapy with diet

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Administered as a once-weekly subcutaneous injection, tirzepatide works through dual incretin receptor activation, enhancing insulin secretion in a glucose-dependent manner whilst suppressing glucagon release and delaying gastric emptying