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While these findings dont directly translate to humans, they raise legitimate concerns about reproductive health, endocrine disruption, and metabolic stress with prolonged, high-dose usage

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Yet, this interaction might also result in increased levels of reactive hydroperoxides from these ions, eventually generating harmful free radicals ( 5 The role of antioxidants in the treatment of kidney stones 5.1 The role of SOD in the treatment of kidney stones Superoxide Dismutase (SOD) is a crucial antioxidant enzyme in cells, playing a pivotal role in shielding them from oxidative stress damage ( 2 ) and hydroperoxide (H 2 O 2 ), aiding in the reduction of intracellular superoxide levels ( Kang et al

University of Colorado Anschutz Medical Campus

NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential