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Cigarette smoke extract, which would be comparable to ST extracts in terms of constituents, fed daily ad libitum to mice was shown to cause a reduction in diameter of zona pellucida-free oocyte and perturbations in morphology of first polar body implying the potency of tobacco extracts to decrease the size and quality of oocytes (Mai et al., 2014)
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Oral spit tobacco: addiction, prevention and treatment
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