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Reads were aligned to the ENSEMBL Homo_sapiens.GRCh38.dna.primary_assembly genome using the ENSEMBL Homo_sapiens.GRCh38.100 transcript [82] annotation file with STAR [83] splice-aware RNA-seq alignment tool in paired mode allowing maximum multimapping of 3

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Time will tell the extent to which [the new products] might help some smokers quit smoking, Kozlowski said, but for that to be a win for health, they will need to also stop using the reduced nicotine cigarettes at some point. Gelbart says if someone really wants to overcome their nicotine addiction, their goal should be abstinence

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