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via Reuters "Investors were most encouraged by the performance of the lower 4 mg dose of retatrutide, which produced roughly 19% weight loss, comparable to the highest dose of current blockbuster therapy Zepbound." #pharmacy #GLP #healthcare To view or add a comment, sign in The most interesting part of Pfizers latest obesity data isnt the 12.3% placebo-adjusted weight loss, its the fact that it was achieved while transitioning patients to once-monthly dosing

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Long-term treatment and follow-up may be required to maintain progress

NHS England and NICE have proposed a 20 million threshold : if a new drug is expected to cost the NHS more than 20m per year in the first 3 years, it triggers mandatory negotiation of access schemes to manage uptake ( [23] )

doi:10.1016/j.biochi.2016.02.012 [PubMed] [Elsevier] 119